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Toste group reports breakthrough in producing chiral compounds

Professor Dean Toste

Professor Dean Toste

August 06, 2007

Chemistry professor Dean Toste has achieved a breakthrough in the design of catalysts that selectively produce chiral compounds. Toste and co-workers report in Science magazine that the catalyst molecule doesn't need to do all the chiral work itself. Using chiral anions to influence chirality in metal-catalyzed reactions has been reported before, but this is the first time anyone has achieved such high enantioselectivities with this strategy, says Toste.







More Information

C&EN:
http://pubs.acs.org/cen/news/85/i31/8531notw8.html

Chemistry World:
http://www.rsc.org/chemistryworld/News/2007/July/26070702.asp

Science:
http://www.sciencemag.org/cgi/content/full/317/5837/496

Nature: (see third summary from the top)
http://www.nature.com/nature/journal/v448/n7153/full/448514a.html

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